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The only available treatment is to decrease muscle tone by rhizotomy or intrathecal baclofen, both of which cause or bring out muscle weakness.

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in another study, a slight increase in resorption rates was observed in rabbits receiving 10 and 15 mg kg day of oral baclofen.

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because baclofen is relatively inexpensive and produces such an intense sedative effect, there is a good potential for drug abuse when using this drug, and withdrawal when the drug is stopped abruptly.

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baclofen tablets are useful for the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity.


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