Arimidex has not been studied in patients with severe hepatic impairment see use in specific populations 8.
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arimidex is approved for the first line treatment of locally advanced or metastatic breast cancer in postmenopausal women, treatment of advanced breast cancer in postmenopausal patients with progression of disease after tamoxifen nolvadex treatment, and as an adjuvant treatment of early hormone receptor positive breast cancer in patients that are postmenopausal.
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patients with pre-existing ischemic heart disease should be informed that an increased incidence of cardiovascular events has been observed with arimidex use compared to tamoxifen use.
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note arimidex is not the only way to clinically lower estradiol.
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